Can use of probiotics drugs cause fungemia? – a literature review

Commercially, there are many products sold as probiotics composed by Sacharomyces boulardii, with probiotic drugs being those that widely used in different clinical situations. The efficacy of these agents is proven studies, well their safety normal use However, have been some reports fungemias related to the hospitals associated factors. Therefore, our objective review knowledge about this association, focusing on factors provide it and development mechanisms. For fungemia probiotics, observed has greater potential patients using a central venous catheter. Although main factor, others reduce patient's immune status, intestinal defense barriers, contribute process, increasing risk fungemia. Despite well-documented benefits must be carefully evaluated for each patient, due associate developing bloodstream infection S. boulardii. It necessary, therefore, include protocols generate alerts establish preventive measures.